Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19946447 | 0.96 | ABCB1 (0.48) | ABCB1ALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL2681809 | 0.96 | ABCB1 (0.48) | ABCB1ALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL27797503 | 0.91 | ABCB1 (0.52) | ABCB1HPGDTAS1R3TAS1R1CYP3A4 | |
| SCHEMBL27818646 | 0.88 | ABCB1 (0.44) | ABCB1CYP3A4CYP2C19 | |
| SCHEMBL2684282 | 0.87 | ABCB1 (0.58) | ABCB1ALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL29786241 | 0.87 | ABCB1 (0.58) | ABCB1ALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL2684130 | 0.87 | ABCB1 (0.58) | ABCB1ALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL14763458 | 0.87 | ABCB1 (0.58) | ABCB1ALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL27818695 | 0.86 | ABCB1 (0.41) | ABCB1TAS1R3TAS1R1CYP3A4 | |
| SCHEMBL2684019 | 0.86 | ABCB1 (0.49) | ABCB1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101848887-A | Chiral diacylhydrazine ligands for modulating exogenous gene expression via ecdysone receptor complexes | INTREXON CORP | 2010-09-29 | — | — | CN | claimed |
| CN-101848887-A | Chiral diacylhydrazine ligands for modulating exogenous gene expression via ecdysone receptor complexes | INTREXON CORP | 2010-09-29 | — | — | CN | disclosed |