Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779356 | 0.96 | TAS1R3 (0.44) | TAS1R3TAS1R1PKMABCB1CYP3A4 | |
| SCHEMBL2682439 | 0.96 | TAS1R3 (0.44) | TAS1R3TAS1R1PKMABCB1CYP3A4 | |
| SCHEMBL2681891 | 0.90 | ABCB1 (0.43) | ABCB1CYP3A4 | |
| SCHEMBL2682545 | 0.90 | ABCB1 (0.43) | ABCB1CYP3A4 | |
| SCHEMBL19946436 | 0.90 | ABCB1 (0.43) | ABCB1CYP3A4 | |
| SCHEMBL27818653 | 0.90 | ABCB1 (0.43) | ABCB1CYP3A4 | |
| SCHEMBL28789040 | 0.86 | ABCB1 (0.46) | TAS1R3TAS1R1ABCB1CYP3A4 | |
| SCHEMBL2682521 | 0.85 | ABCB1 (0.47) | TAS1R3TAS1R1ABCB1CYP3A4 | |
| SCHEMBL14763701 | 0.85 | ABCB1 (0.47) | TAS1R3TAS1R1ABCB1CYP3A4 | |
| SCHEMBL27797503 | 0.84 | ABCB1 (0.52) | TAS1R3TAS1R1ABCB1CYP3A4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101848887-A | Chiral diacylhydrazine ligands for modulating exogenous gene expression via ecdysone receptor complexes | INTREXON CORP | 2010-09-29 | — | — | CN | claimed |
| CN-101848887-A | Chiral diacylhydrazine ligands for modulating exogenous gene expression via ecdysone receptor complexes | INTREXON CORP | 2010-09-29 | — | — | CN | disclosed |