Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29013777 | 0.90 | MAPT (0.42) | MAPTGAASMN1; SMN2RAB9AP2RX4 | |
| SCHEMBL8330072 | 0.87 | MAPT (0.47) | MAPTGAASMN1; SMN2RAB9AP2RX4 | |
| Hydrochloric Acid SCHEMBL8332139 | 0.86 | MAPT (0.45) | MAPTGAASMN1; SMN2RAB9AP2RX4 | |
| SCHEMBL27661234 | 0.86 | MAPT (0.45) | MAPTGAASMN1; SMN2RAB9AP2RX4 | |
| SCHEMBL858689 | 0.86 | MAPT (0.45) | MAPTGAASMN1; SMN2RAB9AP2RX4 | |
| SCHEMBL14691822 | 0.86 | MAPT (0.45) | MAPTGAASMN1; SMN2RAB9AP2RX4 | |
| SCHEMBL8672572 | 0.85 | MAPT (0.38) | MAPTGAASMN1; SMN2RAB9AP2RX4 | |
| Hydrochloric Acid SCHEMBL27291094 | 0.84 | MAPT (0.44) | MAPTGAASMN1; SMN2RAB9AP2RX4 | |
| SCHEMBL9388336 | 0.83 | KMT2A (0.44) | MAPTGAARAB9A | |
| SCHEMBL9935617 | 0.82 | MAPT (0.54) | MAPTGAASMN1; SMN2RAB9AP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773268-A | Preparation process and equipment of ivabradine intermediate benzoazepine ketone skeleton | 新沂市法斯特医药科技有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-111995576-A | Process for preparing polysubstituted nitrogen-containing heterocyclic compound | 三峡大学 | 2020-11-27 | — | — | CN | claimed |
| CN-103130717-A | Preparation method of 2-benzo diazepine anthrone | SHANGHAI B & C CHEMICAL CO LTD | 2013-06-05 | — | — | CN | claimed |
| CN-116283777-A | Synthesis method of fluorine-containing benzo [ b ] azepin-5-ketone compound | 盐城工学院 | 2023-06-23 | — | — | CN | disclosed |
| CN-114989085-A | Aryl lactam ring compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-114773268-A | Preparation process and equipment of ivabradine intermediate benzoazepine ketone skeleton | 新沂市法斯特医药科技有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114773268-A | Preparation process and equipment of ivabradine intermediate benzoazepine ketone skeleton | 新沂市法斯特医药科技有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114773268-A | Preparation process and equipment of ivabradine intermediate benzoazepine ketone skeleton | 新沂市法斯特医药科技有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114749119-A | Intermediate continuous preparation device for ivabradine | 新沂市法斯特医药科技有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114057716-A | Benzazepinone compound and salt thereof, preparation method and medical application thereof | 承德医学院 | 2022-02-18 | — | — | CN | disclosed |
| CN-114057716-A | Benzazepinone compound and salt thereof, preparation method and medical application thereof | 承德医学院 | 2022-02-18 | — | — | CN | disclosed |
| CN-111995576-A | Process for preparing polysubstituted nitrogen-containing heterocyclic compound | 三峡大学 | 2020-11-27 | — | — | CN | disclosed |
| CN-103497181-B | As the benzazepine ketone compounds of glycogen phosphorylase inhibitors, its preparation method and medicinal use | CHENGDE MEDICAL UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |
| CN-104370849-A | N-aryldibenzooxyazacyclooctanone compounds and preparation method thereof | CAS GUANGZHOU CHEMISTRY CO LTD | 2015-02-25 | — | — | CN | disclosed |
| CN-103130717-A | Preparation method of 2-benzo diazepine anthrone | SHANGHAI B & C CHEMICAL CO LTD | 2013-06-05 | — | — | CN | disclosed |
| CN-101861319-A | Benzazepinone compound | UBE INDUSTRIES | 2010-10-13 | — | — | CN | disclosed |