Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29013777 | 0.78 | MAPT (0.42) | KMT2AKDM4ELMNAL3MBTL1NAPRT | |
| SCHEMBL28619553 | 0.77 | ALDH1A1 (0.38) | KMT2AKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL8330072 | 0.76 | MAPT (0.47) | KMT2AKDM4ELMNANAPRTALDH1A1 | |
| SCHEMBL14691822 | 0.74 | MAPT (0.45) | KMT2ALMNAALDH1A1MAPTGAA | |
| Hydrochloric Acid SCHEMBL8332139 | 0.74 | MAPT (0.45) | KMT2AKDM4ELMNANAPRTALDH1A1 | |
| SCHEMBL858689 | 0.74 | MAPT (0.45) | LMNAL3MBTL1TSHRMAPTGAA | |
| SCHEMBL8672572 | 0.73 | MAPT (0.38) | KMT2ALMNAALDH1A1MAPTGAA | |
| SCHEMBL9935617 | 0.71 | MAPT (0.54) | MAPTGAARAB9A | |
| SCHEMBL28529505 | 0.71 | MAPT (0.41) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL28880924 | 0.69 | MAPT (0.42) | KDM4ELMNAL3MBTL1P4HTMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994014796-A1 | NOVEL N-(PYRIDYLCARBONYL)BENZAZEPINE DERIVATIVE AND INTERMEDIATE THEREFOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-07-07 | — | — | WO | disclosed |