Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839205 | 0.85 | TSHR (0.54) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL838394 | 0.79 | RAB9A (0.60) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL838669 | 0.79 | RAB9A (0.60) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL839447 | 0.79 | RAB9A (0.53) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL838342 | 0.79 | RAB9A (0.53) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL838343 | 0.79 | RAB9A (0.53) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL838393 | 0.78 | RAB9A (0.51) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL838587 | 0.78 | RAB9A (0.51) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL27819813 | 0.77 | RAB9A (0.62) | RAB9AMAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL838748 | 0.76 | RAB9A (0.55) | RAB9AMAPTNPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102171213-A | Pyrazolo [3, 4] pyrimidin-4-yl derivatives and their uses to treat diabetes and obesity | ASTRAZENECA AB | 2011-08-31 | — | — | CN | disclosed |