⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588937 | 0.74 | — | — | |
| SCHEMBL8584460 | 0.71 | — | — | |
| SCHEMBL10520401 | 0.69 | GABRA1 (0.33) | — | |
| SCHEMBL4232819 | 0.67 | — | — | |
| SCHEMBL1037142 | 0.67 | — | — | |
| SCHEMBL8665573 | 0.67 | — | — | |
| SCHEMBL10482970 | 0.62 | — | — | |
| SCHEMBL16719716 | 0.62 | — | — | |
| SCHEMBL1140200 | 0.62 | — | — | |
| SCHEMBL2360405 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5495031-A | Process for the production of 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1996-02-27 | — | — | US | claimed |
| US-5495032-A | AMINATION OF THE CORRESPONDING HALOGEN CONTAINING COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1996-02-27 | — | — | US | claimed |
| US-5457096-A | Antibiotic | AMERICAN CYANAMID COMPANY (US) | 1995-10-10 | — | — | US | claimed |
| US-5371076-A | ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | claimed |
| US-8835125-B2 | Methods and compositions for selective labeling of different biotinylated targets within multicolor or multilabel assays | AFFYMETRIX, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8729251-B2 | Parallel preparation of high fidelity probes in an array format | AFFYMETRIX, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-20130197208-A1 | Parallel Preparation of High Fidelity Probes in an Array Format | AFFYMETRIX, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-8338585-B2 | Parallel preparation of high fidelity probes in an array format | AFFYMETRIX, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338093-B2 | Primer array synthesis and validation | AFFYMETRIX, INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20120226027-A1 | Methods and Compositions for Selective Labeling of Different Biotinylated Targets within Multicolor or Multilabel Assays | AFFYMETRIX, INC. (US) | 2012-09-06 | — | — | US | disclosed |
| US-20120184467-A1 | Parallel Preparation of High Fidelity Probes in an Array Format | AFFYMETRIX, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| US-8133987-B2 | Primer array synthesis and validation | AFFYMETRIX, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| EP-0357571-B1 | Pyrimidine nucleosides | MEDIVIR AB (SE) | 1996-04-03 | — | — | EP | disclosed |
| EP-0691333-A2 | Pyrimidine derivatives, process for their preparation and their use as precursors | Medivir Aktiebolag (SE) | 1996-01-10 | — | — | EP | disclosed |
| US-5440040-A | Drug for Aids therapy; viricides | MEDIVIR AB (SE) | 1995-08-08 | — | — | US | disclosed |
| EP-0357571-A2 | Pyrimidine nucleosides | Medivir Aktiebolag (SE) | 1990-03-07 | — | — | EP | disclosed |
| WO-1989012061-A1 | PYRIMIDINE NUCLEOSIDES AND INTERMEDIATES | MEDIVIR AB (SE) | 1989-12-14 | — | — | WO | disclosed |
| EP-0072013-B1 | PYRROLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | MERCK & CO. INC. (US) | 1986-04-16 | — | — | EP | disclosed |
| US-4434175-A | 5-AROYL-PYRROLE ALKANOIC ACIDS | MERCK & CO., INC. (US) | 1984-02-28 | — | — | US | disclosed |
| EP-0072013-A1 | Pyrrole compounds as anti-inflammatory and analgesic agents | MERCK & CO. INC. (US) | 1983-02-16 | — | — | EP | disclosed |