Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.40 |
| ▸ | SRC | P12931 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686825 | 0.88 | FGFR1 (0.48) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL28349555 | 0.78 | SETD7 (0.40) | ALDH1A1SMN1; SMN2TSHRMEN1HPGD | |
| SCHEMBL6686810 | 0.77 | TSHR (0.50) | ALDH1A1SMN1; SMN2TSHRMEN1HPGD | |
| SCHEMBL28049044 | 0.77 | — | — | |
| SCHEMBL28040679 | 0.75 | — | — | |
| SCHEMBL27960566 | 0.75 | — | — | |
| SCHEMBL27874172 | 0.75 | — | — | |
| SCHEMBL27890437 | 0.74 | — | — | |
| SCHEMBL27819207 | 0.72 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL6421365 | 0.72 | NPSR1 (0.38) | FGFR1FGFR2FGFR4FGFR3SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102180883-B | Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof | UNIV YANGZHOU | 2013-04-17 | — | — | CN | claimed |
| CN-102180883-A | Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof | UNIV YANGZHOU | 2011-09-14 | — | — | CN | claimed |
| CN-102180883-B | Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof | UNIV YANGZHOU | 2013-04-17 | — | — | CN | disclosed |
| CN-102180883-A | Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof | UNIV YANGZHOU | 2011-09-14 | — | — | CN | disclosed |