Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31266480 | 0.79 | TSHR (0.41) | — | |
| SCHEMBL8668525 | 0.77 | DPP4 (0.50) | DPP4 | |
| SCHEMBL1426213 | 0.72 | DPP4 (0.46) | DPP4 | |
| SCHEMBL9546085 | 0.70 | — | — | |
| SCHEMBL28309756 | 0.70 | DPP4 (0.43) | DPP4 | |
| SCHEMBL1129965 | 0.69 | DPP4 (0.42) | DPP4 | |
| SCHEMBL28790223 | 0.68 | TSHR (0.34) | — | |
| SCHEMBL1762574 | 0.67 | TSHR (0.31) | — | |
| SCHEMBL27823939 | 0.67 | THRB (0.32) | — | |
| SCHEMBL4422206 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102333777-B | Nitrogen-containing fused heterocyclic compounds and their use as beta-amyloid production inhibitors | EISAI R&D MAN CO LTD | 2014-06-25 | — | — | CN | disclosed |
| CN-102333777-A | Nitrogen-containing fused heterocyclic compounds and their use as beta-amyloid production inhibitors | EISAI R&D MAN CO LTD | 2012-01-25 | — | — | CN | disclosed |