SCHEMBL27824403

SCHEMBL27824403

Cc1cn(On2cc(C)c(N)nc2=O)c(=O)nc1N

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ EP300 Q09472 2/20 0.33
▸ GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27981432 0.83 GAA (0.33) EP300GAA
SCHEMBL27997587 0.79 EP300 (0.32) EP300
SCHEMBL7162791 0.78 PIK3CA (0.38) EP300
SCHEMBL27581641 0.78 EP300 (0.32) EP300
SCHEMBL17041803 0.77 EP300 (0.33) EP300GAA
SCHEMBL27547715 0.76 ALB (0.38) EP300
SCHEMBL4254350 0.75 EP300 (0.34) EP300GAA
SCHEMBL15456757 0.73 EP300 (0.34) EP300
SCHEMBL19841640 0.73 EP300 (0.34) EP300
SCHEMBL20417747 0.71 EP300 (0.30) EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110249053-A COMBINATION THERAPY FOR C3 INHIBITION 阿佩利斯制药有限公司 2019-09-17 — — CN disclosed
CN-105531379-A Quantum molecular sequencing (QM-SEQ): identification of unique nanoelectron tunneling spectroscopy fingerprints modified by DNA, RNA and mononucleotide UNIV COLORADO REGENTS 2016-04-27 — — CN disclosed
CN-101980712-B Targeting microRNAs for the treatment of liver cancer REGULUS THERAPEUTICS INC 2015-02-18 — — CN disclosed
CN-104267011-A Transgenic sheep oocyte screening method NORTHEAST INST GEO & AGROECOLO 2015-01-07 — — CN disclosed
CN-104237533-A Method for preliminarily screening transgenic ewe capable of breeding offspring NORTHEAST INST GEO & AGROECOLO 2014-12-24 — — CN disclosed
CN-101980712-A Targeting microRNAs for the treatment of liver cancer REGULUS THERAPEUTICS INC 2011-02-23 — — CN disclosed
Send feedback