Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.34 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028191 | 0.81 | FDPS (0.51) | FDPSBTN3A1CA12GGPS1CA2 | |
| SCHEMBL1029369 | 0.80 | FDPS (0.50) | FDPSBTN3A1CA12GGPS1CA2 | |
| SCHEMBL1027186 | 0.80 | FDPS (0.50) | FDPSBTN3A1CA12GGPS1CA2 | |
| Zinc Ion SCHEMBL1027185 | 0.76 | FDPS (0.43) | FDPSBTN3A1CA12GGPS1CA2 | |
| SCHEMBL1029368 | 0.76 | FDPS (0.43) | FDPSBTN3A1CA12GGPS1CA2 | |
| SCHEMBL1083518 | 0.70 | FDPS (0.49) | FDPSBTN3A1CA12GGPS1CA2 | |
| SCHEMBL1157059 | 0.69 | GGPS1 (0.47) | FDPSBTN3A1CA12GGPS1CA2 | |
| SCHEMBL17777269 | 0.68 | FDPS (0.66) | FDPSBTN3A1CA12GGPS1CA2 | |
| SCHEMBL1028197 | 0.63 | FDPS (0.58) | FDPSBTN3A1CA12GGPS1CA2 | |
| SCHEMBL27891388 | 0.62 | CHRM5 (0.37) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046152-A | Pharmaceutical compositions containing bisphosphonates | NOVARTIS AG | 2011-05-04 | — | — | CN | disclosed |