SCHEMBL27827554

SCHEMBL27827554

Br[Mg]Br.CCOc1c[c]ccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.41
LTA4H P09960 2/20 0.41
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 2/20 0.35
TSHR P16473 1/20 0.35
RELA Q04206 1/20 0.34
KDM4E B2RXH2 3/20 0.33
ADRA2A P08913 2/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128508 0.92
SCHEMBL27532798 0.90 NQO1 (0.46) NQO1LTA4HTP53CYP3A4TDP1
SCHEMBL28268076 0.90 NQO1 (0.46) NQO1LTA4HTP53CYP3A4TDP1
SCHEMBL27881315 0.90 NQO1 (0.46) NQO1LTA4HTP53CYP3A4TDP1
SCHEMBL28088121 0.85 NQO1 (0.41) NQO1LTA4HTP53CYP3A4TDP1
SCHEMBL920898 0.80 LTA4H (0.63) NQO1LTA4HTP53CYP3A4TDP1
SCHEMBL28886887 0.80 KMT2A (0.36) LTA4HTSHRKDM4ECYP1A2MAPK1
SCHEMBL27359002 0.79 CA4 (0.41) LTA4HCYP3A4CYP1A2ALDH1A1
SCHEMBL27810352 0.77 MAOB (0.51) CYP1A2CYP2C19SMN1; SMN2GAAMAPT
SCHEMBL921385 0.77 TP53 (0.47) NQO1LTA4HTP53CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102050837-A Method for synthesizing tri(m-ethoxyphenyl)bismuthine YUJIE JI 2011-05-11 CN disclosed