Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491069 | 0.84 | APP (0.42) | EPHX2PPARDPPARA | |
| SCHEMBL18174187 | 0.79 | CYP4F2 (0.51) | EPHX2HCRTR1HCRTR2 | |
| SCHEMBL1569028 | 0.76 | EPHX2 (0.45) | EPHX2PPARAHCRTR1HCRTR2PDE2A | |
| SCHEMBL13557302 | 0.75 | PDE2A (0.44) | EPHX2HCRTR1HCRTR2PDE2A | |
| SCHEMBL27793355 | 0.75 | CYP4F2 (0.39) | EPHX2 | |
| SCHEMBL27828877 | 0.75 | PDE2A (0.47) | EPHX2PDE2A | |
| SCHEMBL27788071 | 0.74 | DAO (0.43) | HTTPPARDPPARANAAA | |
| SCHEMBL16961446 | 0.73 | FFAR1 (0.52) | EPHX2PPARDPPARA | |
| SCHEMBL8745263 | 0.72 | EPHX2 (0.47) | EPHX2CACNA1HHCRTR1HCRTR2PDE2A | |
| SCHEMBL18174237 | 0.72 | EPHX2 (0.49) | EPHX2CACNA1HHCRTR1HCRTR2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102056920-A | Tetrazole compounds as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2011-05-11 | — | — | CN | disclosed |