Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1569028 | 0.90 | EPHX2 (0.45) | EPHX2PDE2AP2RX7KCNH2TMEM97 | |
| SCHEMBL2447332 | 0.86 | EPHX2 (0.50) | EPHX2PDE2AP2RX7HCRTR1HCRTR2 | |
| SCHEMBL8926703 | 0.83 | EPHX2 (0.44) | EPHX2PDE2AP2RX7KCNH2TMEM97 | |
| SCHEMBL13557302 | 0.83 | PDE2A (0.44) | EPHX2PDE2AKCNH2TMEM97SIGMAR1 | |
| SCHEMBL16961446 | 0.81 | FFAR1 (0.52) | EPHX2 | |
| SCHEMBL8430299 | 0.80 | P2RX7 (0.41) | EPHX2P2RX7KCNH2TMEM97SIGMAR1 | |
| SCHEMBL18174237 | 0.80 | EPHX2 (0.49) | EPHX2PDE2AP2RX7HCRTR1HCRTR2 | |
| SCHEMBL1568961 | 0.79 | EPHX2 (0.44) | EPHX2PDE2AP2RX7HCRTR1HCRTR2 | |
| SCHEMBL25182236 | 0.79 | EPHX2 (0.50) | EPHX2PDE2AP2RX7HCRTR1HCRTR2 | |
| SCHEMBL1241032 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |