Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28794188 | 0.91 | MET (0.52) | METMAPTTP53 | |
| SCHEMBL27830003 | 0.85 | MET (0.56) | METTP53KCNH2 | |
| SCHEMBL2385103 | 0.85 | MET (0.55) | METMAPTTP53 | |
| SCHEMBL28794190 | 0.77 | MET (0.52) | METMAPTTP53 | |
| SCHEMBL2385467 | 0.76 | MET (0.58) | METKCNH2 | |
| SCHEMBL2386229 | 0.76 | PRKD3 (0.62) | MET | |
| SCHEMBL2387244 | 0.76 | MET (0.69) | METTP53KCNH2 | |
| SCHEMBL2387752 | 0.75 | MET (0.52) | MET | |
| SCHEMBL2387593 | 0.75 | MET (0.71) | METTP53KCNH2 | |
| SCHEMBL2386733 | 0.75 | MET (0.64) | METKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101910158-A | Pyridine and pyrazine derivatives useful in the treatment of cell proliferative disorders | ASTRAZENECA AB | 2010-12-08 | — | — | CN | disclosed |