Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063592 | 0.81 | CNR2 (0.49) | SMN1; SMN2 | |
| SCHEMBL6628999 | 0.81 | CNR2 (0.49) | SMN1; SMN2 | |
| SCHEMBL16148135 | 0.81 | TAAR1 (0.51) | TAAR1FFAR1FFAR4NPC1RAB9A | |
| SCHEMBL16148136 | 0.81 | TAAR1 (0.51) | TAAR1FFAR1FFAR4NPC1RAB9A | |
| SCHEMBL25173384 | 0.81 | TSHR (0.51) | TAAR1FFAR1FFAR4NPC1RAB9A | |
| SCHEMBL8644326 | 0.75 | CYSLTR2 (0.49) | TAAR1PTGESKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6586 | 0.74 | FFAR1 (0.68) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL3471743 | 0.74 | HCAR2 (0.47) | TAAR1FFAR1FFAR4HCAR2NPC1 | |
| SCHEMBL14542694 | 0.73 | TAAR1 (0.50) | TAAR1 | |
| SCHEMBL3456103 | 0.73 | TAAR1 (0.50) | TAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083839-A | Compound (I) | ASTRAZENECA AB | 2011-06-01 | — | — | CN | disclosed |