SCHEMBL27831069

SCHEMBL27831069

OC1c2ccccc2-c2ccc(-c3ccccc3)cc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.47
HTR2B P41595 4/20 0.46
HTR7 P34969 2/20 0.46
DYRK1A Q13627 1/20 0.45
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
APAF1 O14727 1/20 0.44
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
XBP1 P17861 1/20 0.44
PTBP1 P26599 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
GALK1 P51570 1/20 0.44
BLM P54132 1/20 0.44
SMAD3 P84022 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28794504 0.87 PDK2 (0.53) PDK2HTR2BHTR7DYRK1AMEN1
SCHEMBL30719676 0.82 EDNRB (0.46) MEN1MAPTKMT2ASMN1; SMN2APAF1
SCHEMBL30673022 0.81 MAPT (0.46) HTR2BHTR7DYRK1AMAPTSMN1; SMN2
SCHEMBL18385982 0.79 HTR2B (0.50) HTR2BHTR7DYRK1AMEN1MAPT
SCHEMBL29884836 0.78 MAOA (0.52) HTR2BHTR7DYRK1AMEN1MAPT
SCHEMBL29376368 0.78 MAOA (0.52) HTR2BHTR7DYRK1AMEN1MAPT
SCHEMBL216862 0.78 MAOA (0.52) HTR2BHTR7DYRK1AMEN1MAPT
SCHEMBL27810529 0.78 EDNRB (0.49) HTR2BHTR7DYRK1AMEN1MAPT
SCHEMBL27810520 0.77 MEN1 (0.44) PDK2MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL27688305 0.76 MAOA (0.50) HTR2BHTR7DYRK1AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102093158-A Fluorene-anthracene compound for preparing luminescent materials and synthesis method thereof UNIV SHANGHAI 2011-06-15 CN disclosed