Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784369 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HSD17B10CYP3A4ALOX15CASP1 | |
| SCHEMBL2783950 | 0.92 | SMN1; SMN2 (0.42) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2783869 | 0.92 | SMN1; SMN2 (0.42) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2784728 | 0.92 | SMN1; SMN2 (0.42) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2784101 | 0.89 | SMN1; SMN2 (0.40) | ALDH1A1HSD17B10CYP3A4ALOX15CASP1 | |
| SCHEMBL2784474 | 0.89 | SMN1; SMN2 (0.44) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2784132 | 0.87 | MEN1 (0.42) | ALDH1A1HSD17B10CYP3A4ALOX15CASP1 | |
| SCHEMBL2786121 | 0.87 | SMN1; SMN2 (0.43) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2785773 | 0.86 | SMN1; SMN2 (0.38) | ALDH1A1HSD17B10CYP3A4ALOX15CASP1 | |
| SCHEMBL2784478 | 0.86 | SMN1; SMN2 (0.40) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130085237-A1 | Fluorinated Diamine and Polymer Formed Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2013-04-04 | — | — | US | disclosed |
| US-20100029895-A1 | Fluorinated Diamine and Polymer Formed Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029895-A1 | Fluorinated Diamine and Polymer Formed Therefrom | AFF2, AFF1, AFF4 | ALDH1A1 931/4885HSD17B10 3598/4885CYP3A4 3797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.