Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449893 | 0.83 | AAK1 (0.34) | MMP13HDAC6HDAC1HDAC2AAK1 | |
| SCHEMBL4794923 | 0.83 | AAK1 (0.34) | MMP13HDAC6HDAC1HDAC2AAK1 | |
| SCHEMBL23299364 | 0.81 | HDAC6 (0.36) | MMP13HDAC6HDAC1HDAC2AAK1 | |
| SCHEMBL643632 | 0.80 | AAK1 (0.35) | MMP13HDAC6HDAC1HDAC2AAK1 | |
| SCHEMBL6275735 | 0.78 | DGAT1 (0.35) | MMP13HDAC6HDAC1HDAC2AAK1 | |
| SCHEMBL17277663 | 0.78 | AAK1 (0.32) | MMP13HDAC6HDAC1HDAC2AAK1 | |
| SCHEMBL27789144 | 0.78 | HDAC6 (0.34) | MMP13HDAC6HDAC1HDAC2AAK1 | |
| SCHEMBL27789228 | 0.78 | HDAC6 (0.34) | MMP13HDAC6HDAC1HDAC2AAK1 | |
| SCHEMBL5345861 | 0.77 | AAK1 (0.35) | MMP13HDAC6HDAC1HDAC2AAK1 | |
| SCHEMBL24488616 | 0.77 | AAK1 (0.33) | MMP13HDAC6HDAC1HDAC2AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102307903-A | Novel semi-synthetic glycopeptides as antibacterial agents | LEAD THERAPEUTICS INC | 2012-01-04 | — | — | CN | disclosed |