Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2782224 | 0.90 | FAAH (0.61) | FAAH | |
| SCHEMBL711231 | 0.85 | FAAH (0.78) | FAAH | |
| SCHEMBL2781373 | 0.84 | FAAH (0.67) | FAAH | |
| SCHEMBL2780227 | 0.84 | FAAH (0.55) | FAAH | |
| SCHEMBL2783159 | 0.84 | FAAH (0.55) | FAAH | |
| SCHEMBL2781072 | 0.83 | FAAH (0.53) | FAAH | |
| SCHEMBL2782417 | 0.83 | FAAH (0.55) | FAAH | |
| SCHEMBL2780983 | 0.83 | FAAH (0.58) | FAAH | |
| SCHEMBL2781943 | 0.83 | FAAH (0.52) | FAAH | |
| SCHEMBL2782400 | 0.82 | FAAH (0.55) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161997-A1 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | Boger, Dale L. (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008150492-A1 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-12-11 | — | — | WO | disclosed |