Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871761 | 0.91 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1MAPK1SLC15A1TDP1 | |
| SCHEMBL111605 | 0.91 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1MAPK1SLC15A1TDP1 | |
| Hydrochloric Acid SCHEMBL27438937 | 0.89 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1MAPK1SLC15A1TDP1 | |
| SCHEMBL27168266 | 0.89 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1MAPK1SLC15A1TDP1 | |
| Ammonia Solution, Strong SCHEMBL3117410 | 0.89 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1MAPK1SLC15A1TDP1 | |
| Propionic Acid SCHEMBL18954211 | 0.87 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1TDP1KMT2A | |
| Formaldehyde SCHEMBL28008518 | 0.87 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1SLC15A1TDP1 | |
| SCHEMBL29833557 | 0.87 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPK1SLC15A1TDP1 | |
| Biphenyl SCHEMBL27564941 | 0.86 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPK1TDP1KMT2A | |
| SCHEMBL27341710 | 0.86 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPK1SLC15A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083845-A | Cyclopropyl polymerase inhibitors | CENTOCOR ORTHO BIOTECH PRODUCT | 2011-06-01 | — | — | CN | disclosed |