Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442581 | 0.89 | NAAA (0.41) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL6333647 | 0.85 | NAAA (0.47) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL7064626 | 0.85 | NAAA (0.47) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL6442583 | 0.85 | NAAA (0.38) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL8057242 | 0.83 | NAAA (0.45) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL6856910 | 0.82 | NAAA (0.48) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL21834086 | 0.82 | NAAA (0.48) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL1067866 | 0.79 | NAAA (0.41) | NAAACES2EPHX1TSHRLPAR3 | |
| SCHEMBL11477129 | 0.79 | NAAA (0.50) | NAAAEPHX1TSHRDGKAHCAR2 | |
| SCHEMBL10710530 | 0.79 | NAAA (0.50) | NAAAEPHX1TSHRDGKAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102099330-A | Nitric oxide donating prostamides | NICOX SA | 2011-06-15 | — | — | CN | disclosed |