Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176760 | 0.91 | KDR (0.36) | KDRCHEK1FGFR1LCKCDK4 | |
| SCHEMBL176855 | 0.78 | PRKAG1 (0.45) | — | |
| SCHEMBL2305707 | 0.77 | KDR (0.36) | KDRCHEK1FGFR1LCKCDK4 | |
| Tert-Butyl Formate SCHEMBL27831787 | 0.76 | CYP1A2 (0.41) | KDRCHEK1FGFR1LCK | |
| SCHEMBL176764 | 0.76 | TTK (0.37) | KDRCHEK1FGFR1LCKCDK4 | |
| SCHEMBL176962 | 0.75 | KDR (0.35) | KDRCHEK1FGFR1LCKCDK4 | |
| SCHEMBL2237198 | 0.75 | KDR (0.35) | KDRCHEK1FGFR1LCKCDK4 | |
| SCHEMBL2305634 | 0.73 | KDR (0.34) | KDRCHEK1FGFR1LCKCDK4 | |
| SCHEMBL29781791 | 0.72 | CA12 (0.40) | KDRCHEK1FGFR1LCKCDK4 | |
| SCHEMBL17026535 | 0.72 | CA12 (0.40) | KDRCHEK1FGFR1LCKCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102089302-A | Nitrogenated bicyclic heterocyclic compound | ASAHI KASEI PHARMA CORP | 2011-06-08 | — | — | CN | disclosed |