Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL25416326 | 1.00 | SOAT1 (0.61) | SOAT1FAAHMEN1KMT2ATP53 | |
| Palmitamide SCHEMBL25414734 | 1.00 | SOAT1 (0.61) | SOAT1FAAHMEN1KMT2ATP53 | |
| Octadecanoic Acid Amide SCHEMBL25415205 | 1.00 | SOAT1 (0.61) | SOAT1FAAHMEN1KMT2ATP53 | |
| Tetradecanamide SCHEMBL25415970 | 1.00 | SOAT1 (0.61) | SOAT1FAAHMEN1KMT2ATP53 | |
| Diethylamine SCHEMBL7649932 | 1.00 | SOAT1 (0.61) | SOAT1FAAHMEN1KMT2ATP53 | |
| Octadecanoic Acid Amide SCHEMBL3930812 | 0.94 | FAAH (0.55) | SOAT1FAAHMEN1KMT2ATP53 | |
| Diethylamine SCHEMBL28163405 | 0.91 | TP53 (0.48) | SOAT1FAAHMEN1KMT2ATP53 | |
| Octadecanoic Acid Amide SCHEMBL20596883 | 0.90 | FAAH (0.60) | SOAT1FAAHMEN1KMT2ATP53 | |
| SCHEMBL42192 | 0.88 | SOAT1 (0.74) | SOAT1FAAHMEN1KMT2ATP53 | |
| SCHEMBL22319678 | 0.88 | SOAT1 (0.74) | SOAT1FAAHMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102695758-A | Phenyl-containing organopolysiloxane composition, raw cosmetic material, and glossy cosmetic material | DOW CORNING TORAY CO LTD | 2012-09-26 | — | — | CN | disclosed |
| CN-102666664-A | Novel co-modified organopolysiloxane | DOW CORNING TORAY CO LTD | 2012-09-12 | — | — | CN | disclosed |
| CN-102666663-A | Novel organopolysiloxane copolymer | DOW CORNING TORAY CO LTD | 2012-09-12 | — | — | CN | disclosed |
| CN-102648264-A | Thickening or gelling agent for oil-based raw materials | DOW CORNING TORAY CO LTD | 2012-08-22 | — | — | CN | disclosed |
| CN-102639542-A | Linear and cyclic siloxanes and cosmetic compositions made thereof | DOW CORNING TORAY CO LTD | 2012-08-15 | — | — | CN | disclosed |
| CN-101472979-B | Polyether-modified organopolysiloxane, diorganopolysiloxane-polyether block copolymer, processes for producing these, and cosmetic | DOW CORNING TORAY CO LTD | 2012-01-04 | — | — | CN | disclosed |