SCHEMBL27832183

SCHEMBL27832183

Oc1ccccc1-c1ncc(-c2cccnc2)[nH]1

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 16/20 0.63
HPGDS O60760 3/20 0.56
CYP2A6 P11509 1/20 0.53
SCN2A Q99250 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17269679 0.86 SCN2A (0.65) NPY5RHPGDSSCN2A
SCHEMBL27812068 0.85 NPY5R (0.62) NPY5RHPGDSCYP2A6SCN2A
SCHEMBL27832185 0.83 NPY5R (0.64) NPY5RHPGDSCYP2A6
SCHEMBL27815625 0.81 NPY5R (0.87) NPY5RHPGDSCYP2A6SCN2A
SCHEMBL31627417 0.81 NPY5R (0.62) NPY5RHPGDSSCN2A
SCHEMBL28787857 0.80 NPY5R (0.59) NPY5RHPGDSCYP2A6SCN2A
SCHEMBL27832174 0.79 NPY5R (0.67) NPY5RHPGDSCYP2A6SCN2A
SCHEMBL1155160 0.79 ALDH1A1 (0.60) CYP2A6
SCHEMBL30070521 0.79 ALDH1A1 (0.60) CYP2A6
Hydrochloric Acid SCHEMBL21412299 0.77 ALDH1A1 (0.58) CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102089297-A Novel 1,2,4 oxadiazole compounds and methods of use thereof ABBOTT LAB 2011-06-08 CN disclosed