Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.54 |
| ▸ | PPARA | Q07869 | 14/20 | 0.54 |
| ▸ | PPARD | Q03181 | 11/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | EPOR | P19235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27833812 | 0.98 | PPARG (0.56) | PPARGPPARAPPARDRORCFFAR4 | |
| Piperazine SCHEMBL27813776 | 0.93 | PPARG (0.52) | PPARGPPARAPPARDRORCFFAR4 | |
| SCHEMBL27909994 | 0.89 | PPARG (0.55) | PPARGPPARAPPARDRORCEPOR | |
| SCHEMBL28806426 | 0.86 | PPARG (0.58) | PPARGPPARAPPARDRORCEPOR | |
| SCHEMBL27833763 | 0.85 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL27867715 | 0.83 | RORC (0.40) | PPARGPPARAPPARDRORC | |
| SCHEMBL2216331 | 0.82 | PPARG (0.73) | PPARGPPARAPPARDRORC | |
| SCHEMBL2212804 | 0.80 | PPARG (0.77) | PPARGPPARAPPARDRORC | |
| SCHEMBL27733815 | 0.78 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL27713320 | 0.78 | PPARG (0.54) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102112441-B | Use of indole derivatives as NURR-1 activators for the treatment of parkinson's disease | FOURNIER LAB S A | 2013-07-10 | — | — | CN | disclosed |
| CN-102112441-A | Use of indole derivatives as NURR-1 activators for the treatment of parkinson's disease | FOURNIER LAB S A | 2011-06-29 | — | — | CN | disclosed |