Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849454 | 1.00 | HRH3 (0.44) | HRH3KCNH2HAO1THRBSMN1; SMN2 | |
| SCHEMBL29091934 | 0.98 | HRH3 (0.41) | HRH3KCNH2HAO1THRBSMN1; SMN2 | |
| SCHEMBL9136281 | 0.90 | ESR2 (0.38) | HRH3KCNH2HAO1POLBESR2 | |
| SCHEMBL19864914 | 0.81 | ESR2 (0.52) | HRH3KCNH2POLBRAB9AESR2 | |
| SCHEMBL6238498 | 0.81 | HRH3 (0.44) | HRH3KCNH2HAO1THRBSMN1; SMN2 | |
| SCHEMBL20003490 | 0.78 | ESR2 (0.47) | HRH3KCNH2SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6704196 | 0.77 | HAO1 (0.59) | HRH3KCNH2HAO1THRBSMN1; SMN2 | |
| SCHEMBL27460507 | 0.76 | HRH3 (0.46) | HRH3KCNH2HAO1THRBSMN1; SMN2 | |
| SCHEMBL15260520 | 0.76 | HDAC8 (0.52) | HRH3KCNH2HAO1SMN1; SMN2MAPT | |
| SCHEMBL28584923 | 0.76 | HDAC8 (0.52) | HRH3KCNH2HAO1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026963-B | Aromatic dicyanate compounds with high aliphatic carbon content | DOW GLOBAL TECHNOLOGIES INC | 2015-04-22 | — | — | CN | disclosed |
| CN-102026950-B | Ethylenically unsaturated monomers comprising aliphatic and aromatic moieties | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-10-15 | — | — | CN | disclosed |
| CN-102026963-A | Aromatic dicyanate compounds with high aliphatic carbon content | DOW GLOBAL TECHNOLOGIES INC | 2011-04-20 | — | — | CN | disclosed |
| CN-102026950-A | Ethylenically unsaturated monomers comprising aliphatic and aromatic moieties | DOW GLOBAL TECHNOLOGIES INC | 2011-04-20 | — | — | CN | disclosed |