Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620706 | 0.82 | SNCA (0.42) | SNCAALDH1A1GAAHTTL3MBTL1 | |
| SCHEMBL28785824 | 0.79 | SIRT2 (0.41) | ALDH1A1GAAMAPTHTTRXFP1 | |
| SCHEMBL499853 | 0.74 | NOS3 (0.48) | SNCAALDH1A1GAAMAPTHTT | |
| SCHEMBL499453 | 0.74 | NOS3 (0.48) | SNCAALDH1A1GAAMAPTHTT | |
| SCHEMBL499196 | 0.74 | KDM4E (0.45) | SNCAALDH1A1GAACACNA1CMAPT | |
| SCHEMBL499371 | 0.70 | NOS3 (0.50) | SNCAALDH1A1GAAL3MBTL1LMNA | |
| SCHEMBL27605924 | 0.69 | KDM4E (0.42) | ALDH1A1GAAMAPTHTTRXFP1 | |
| SCHEMBL27799198 | 0.69 | SIRT2 (0.41) | ALDH1A1GAAMAPTHTTRXFP1 | |
| SCHEMBL499103 | 0.68 | NOS3 (0.49) | ALDH1A1GAACACNA1CMAPTHTT | |
| SCHEMBL30123443 | 0.67 | SNCA (0.49) | SNCAALDH1A1GAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102143961-A | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON INC | 2011-08-03 | — | — | CN | disclosed |