Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetradecane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecane SCHEMBL27817190 | 1.00 | TP53 (0.44) | TP53RECQLGLAHPGDTSHR | |
| Hexadecane SCHEMBL27817294 | 1.00 | TP53 (0.44) | TP53RECQLGLAHPGDTSHR | |
| Sulfuric Acid SCHEMBL27836713 | 0.90 | LMNA (0.36) | TP53TSHRLMNA | |
| Hexadecane SCHEMBL28792088 | 0.86 | RECQL (0.46) | TP53RECQLGLAHPGDTSHR | |
| Dodecane SCHEMBL27817165 | 0.86 | RECQL (0.46) | TP53RECQLGLAHPGDTSHR | |
| Tetradecane SCHEMBL27836707 | 0.86 | RECQL (0.46) | TP53RECQLGLAHPGDTSHR | |
| Tridecane SCHEMBL28803872 | 0.84 | SPHK1 (0.43) | TSHRMAPTLMNASMPD1 | |
| Tetradecane SCHEMBL27836712 | 0.84 | SPHK1 (0.43) | TSHRMAPTLMNASMPD1 | |
| SCHEMBL27662509 | 0.84 | SPHK1 (0.43) | TSHRMAPTLMNASMPD1 | |
| Dodecane SCHEMBL27817167 | 0.84 | SPHK1 (0.43) | TSHRMAPTLMNASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102105427-A | Particle size diameter range 90) Is greater than 3 μm to about 10 μmAtovaquone of m | ALPHAPHARM PTY LTD | 2011-06-22 | — | — | CN | disclosed |