SCHEMBL278374

SCHEMBL278374

C=C(C)C(=O)OCCCn1c(=O)n(CCCOC(=O)C(=C)C)c(=O)n(CCCOC(=O)C(=C)C)c1=O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
THRB P10828 1/20 0.46
POLB P06746 1/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 5/20 0.40
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.33
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
TNF P01375 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22063822 0.97 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22064164 0.95 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1263149 0.95 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5610090 0.94 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL3249618 0.94 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16694191 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16694184 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9184800 0.90 THRB (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22064162 0.89 POLB (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL150780 0.89 THRB (0.48) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4526920-A Contains poly(meth)acrylic ester of oxy or polyoxyalkane polyol, polymerization initiator, filler MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-02 US claimed
CN-113166419-B Method for preparing multifunctional organosiloxane and composition containing same 美国陶氏有机硅公司 2023-05-09 CN disclosed
CN-113056501-B Multifunctional organosiloxanes, compositions comprising multifunctional organosiloxanes and methods for preparing the same 美国陶氏有机硅公司 2023-03-07 CN disclosed
CN-115698137-A Process for preparing multifunctional organosiloxanes and compositions comprising the same 美国陶氏有机硅公司 2023-02-03 CN disclosed
CN-113056502-B Multifunctional organosiloxanes, compositions comprising multifunctional organosiloxanes and methods for preparing the same 美国陶氏有机硅公司 2023-01-24 CN disclosed
US-11319511-B2 Compositions comprising encapsulates THE PROCTER & GAMBLE COMPANY (US) 2022-05-03 US disclosed
CN-111051461-B Dual cure adhesive compositions and methods of making and using the same 美国陶氏有机硅公司 2022-04-26 CN disclosed
CN-113166419-A Process for preparing multifunctional organosiloxanes and compositions comprising the same 美国陶氏有机硅公司 2021-07-23 CN disclosed
CN-113056501-A Multifunctional organosiloxanes, compositions comprising multifunctional organosiloxanes and methods for preparing the same 美国陶氏有机硅公司 2021-06-29 CN disclosed
CN-113056502-A Multifunctional organosiloxanes, compositions comprising multifunctional organosiloxanes and methods for preparing the same 美国陶氏有机硅公司 2021-06-29 CN disclosed
US-20020028287-A1 Manufacture of optical fiber and optical fiber tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-03-07 US disclosed
EP-1182178-A1 Manufacture of optical fiber and optical fiber tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-02-27 EP disclosed
US-6306502-B1 COMPOSITION COMPRISING ULTRAVIOLET-CURABLE SILICONE, MONOMER MIXTURE COMPRISING TRIS((METH)ACRYLOYLOXYALKYL)ISOCYANURATE AND URETHANE POLY(METH)ACRYLATE HAVING ALICYCLIC SKELETON, PHOTOPOLYMERIZATION INITIATOR MITSUBISHI RAYON CO., LTD. (JP) 2001-10-23 US disclosed
EP-0899091-A2 Transparent coated molded product and method for producing the same Asahi Glass Company Ltd. (JP) 1999-03-03 EP disclosed
EP-0869154-A1 COATING COMPOSITION FORMING WEAR-RESISTANT COAT AND ARTICLE COVERED WITH THE COAT MITSUBISHI RAYON CO., LTD. (JP) 1998-10-07 EP disclosed
US-5693390-A ACRYLIC COATING FOR RETURNABLE BOTTLE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-12-02 US disclosed
US-5369183-A Thermoplastic resin and acrylic ester compound containing dicyclopentadiene type alicyclic ring SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1994-11-29 US disclosed
EP-0423998-A2 Composite and moulded articles therefrom SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1991-04-24 EP disclosed
US-4719149-A DENTISTRY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-01-12 US disclosed
US-4526920-A Contains poly(meth)acrylic ester of oxy or polyoxyalkane polyol, polymerization initiator, filler MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-02 US disclosed