Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14080751 | 1.00 | NOTUM (0.52) | NOTUMNPC1RAB9AATAD2PIK3CA | |
| SCHEMBL245938 | 0.92 | MAPT (0.43) | NOTUMNPC1RAB9AMAPTLMNA | |
| SCHEMBL2517442 | 0.88 | ALDH1A1 (0.35) | NOTUMNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL7996476 | 0.88 | ALDH1A1 (0.35) | NOTUMNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL27979361 | 0.88 | ALDH1A1 (0.35) | NOTUMNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL14562749 | 0.88 | ALDH1A1 (0.35) | NOTUMNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL28807262 | 0.88 | ALDH1A1 (0.35) | NOTUMNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL28180007 | 0.88 | ALDH1A1 (0.35) | NOTUMNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL28062944 | 0.82 | ALDH1A1 (0.31) | NPC1RAB9AALDH1A1MAPK1 | |
| Trimethylammonium SCHEMBL8994460 | 0.82 | GSK3B (0.35) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053812-B | Metal iridium-containing single pyridyl porphyrin crystal material and preparation method thereof | 江苏大学 | 2020-08-28 | — | — | CN | claimed |
| CN-102180883-A | Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof | UNIV YANGZHOU | 2011-09-14 | — | — | CN | claimed |
| CN-113444099-B | Reaction type hydrogen sulfide fluorescent probe and preparation and application thereof | 浙江大学城市学院 | 2022-06-21 | — | — | CN | disclosed |
| CN-113444099-A | Reaction type hydrogen sulfide fluorescent probe and preparation and application thereof | 浙江大学城市学院 | 2021-09-28 | — | — | CN | disclosed |
| CN-109053812-B | Metal iridium-containing single pyridyl porphyrin crystal material and preparation method thereof | 江苏大学 | 2020-08-28 | — | — | CN | disclosed |
| CN-109053812-B | Metal iridium-containing single pyridyl porphyrin crystal material and preparation method thereof | 江苏大学 | 2020-08-28 | — | — | CN | disclosed |
| CN-102167704-B | Water-soluble porphyrin gold (III) anticancer compounds and preparation method thereof | UNIV YANGZHOU | 2014-05-14 | — | — | CN | disclosed |
| CN-102180883-B | Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof | UNIV YANGZHOU | 2013-04-17 | — | — | CN | disclosed |
| CN-102180883-A | Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof | UNIV YANGZHOU | 2011-09-14 | — | — | CN | disclosed |
| CN-102167704-A | Water-soluble porphyrin gold (III) anticancer compounds and preparation method thereof | UNIV YANGZHOU | 2011-08-31 | — | — | CN | disclosed |