Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27819109 | 0.90 | PIK3CA (0.66) | PIK3CAMAPTKMT2AMEN1TP53 | |
| SCHEMBL27858464 | 0.90 | PIK3CA (0.69) | PIK3CAMAPTKMT2AMEN1TP53 | |
| SCHEMBL28795786 | 0.90 | PIK3CA (0.69) | PIK3CAMAPTKMT2AMEN1TP53 | |
| SCHEMBL27858474 | 0.87 | PIK3CA (0.62) | PIK3CAMAPTKMT2AMEN1TP53 | |
| SCHEMBL27840967 | 0.86 | PIK3CA (0.69) | PIK3CAMAPTKMT2AMEN1TP53 | |
| SCHEMBL14488046 | 0.83 | PKM (0.66) | PIK3CAKMT2AMEN1POLBHTT | |
| SCHEMBL27840940 | 0.83 | PIK3CA (0.76) | PIK3CAMAPTKMT2AMEN1HTT | |
| SCHEMBL27841038 | 0.77 | PIK3CA (0.65) | PIK3CAMAPTKMT2AMEN1TP53 | |
| SCHEMBL27838809 | 0.77 | PIK3CA (0.62) | PIK3CAMAPTTP53POLBHTT | |
| SCHEMBL27840956 | 0.77 | PIK3CA (0.61) | PIK3CAMAPTKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250022-B | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2013-10-16 | — | — | CN | claimed |
| CN-102250022-A | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2011-11-23 | — | — | CN | claimed |
| CN-102250022-B | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2013-10-16 | — | — | CN | disclosed |
| CN-102250022-A | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2011-11-23 | — | — | CN | disclosed |