Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.47 |
| ▸ | ALKBH3 | Q96Q83 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017150 | 0.77 | HTR3A (0.58) | BCHEACHEHTR3ATP53AURKA | |
| SCHEMBL27547390 | 0.75 | BCHE (0.56) | BCHEACHEHTR3ATP53AURKA | |
| SCHEMBL9407612 | 0.73 | TP53 (0.56) | BCHEACHEHTR3ATP53AURKA | |
| SCHEMBL17764208 | 0.73 | AURKA (0.50) | BCHEACHEHTR3ATP53AURKA | |
| SCHEMBL6597824 | 0.72 | AOC3 (0.40) | KDM4ERAB9AMAPTHRH4NPC1 | |
| SCHEMBL21047636 | 0.71 | BCHE (0.69) | BCHEACHEHTR3ATP53AURKA | |
| SCHEMBL20472708 | 0.70 | BCHE (0.54) | BCHEACHEHTR3ATP53AURKA | |
| SCHEMBL2674037 | 0.69 | BCHE (0.90) | BCHEACHEHTR3ATP53TRPC3 | |
| SCHEMBL2676103 | 0.69 | BCHE (0.96) | BCHEACHEHTR3ATP53TRPC3 | |
| SCHEMBL21047796 | 0.69 | BCHE (0.60) | BCHEACHEHTR3ATP53AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250082-A | Benzimidazolyl thiazolidinone compounds and synthesis method thereof | FOURTH MILITARY MEDICAL UNIV | 2011-11-23 | — | — | CN | disclosed |
| CN-102250082-A | Benzimidazolyl thiazolidinone compounds and synthesis method thereof | FOURTH MILITARY MEDICAL UNIV | 2011-11-23 | — | — | CN | disclosed |