Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 2/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28391787 | 0.81 | F10 (0.39) | TP53LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL27643493 | 0.75 | ALDH1A1 (0.34) | TP53LMNAALDH1A1MEN1HPGD | |
| SCHEMBL18250280 | 0.75 | CCNT1 (0.38) | TP53LMNAKDM4ETHRBHSP90AA1 | |
| SCHEMBL18250312 | 0.73 | CCNT1 (0.39) | TP53LMNATHRBHSP90AA1HSP90AB1 | |
| SCHEMBL4964108 | 0.72 | KDM4E (0.40) | LMNAKDM4ETHRBPI4KAPI4K2B | |
| SCHEMBL11015922 | 0.72 | KDM4E (0.40) | LMNAKDM4ETHRBPI4KAPI4K2B | |
| SCHEMBL20851567 | 0.72 | F10 (0.41) | LMNAALDH1A1 | |
| SCHEMBL18250691 | 0.70 | KDM4E (0.38) | TP53LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL18250232 | 0.69 | MAP3K12 (0.38) | LMNATHRBHSP90AA1HSP90AB1ADORA2A | |
| SCHEMBL9442396 | 0.68 | PI4KA (0.37) | LMNAALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053558-B | Synthesis method of N-heterocyclic amide derivative | 贵州大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-102216298-B | Imidazopyridines and imidazopyrimidines as HIV-1 reverse transcriptase inhibitors | CSIR INC | 2014-04-16 | — | — | CN | disclosed |
| CN-102216298-A | Imidazopyridines and imidazopyrimidines as HIV-1 reverse transcriptase inhibitors | CSIR | 2011-10-12 | — | — | CN | disclosed |