Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380167 | 0.93 | KIF11 (0.47) | TDO2KIF11PARP14CDK4CCND1 | |
| SCHEMBL30463516 | 0.91 | KIF11 (0.49) | TDO2IDO1KIF11PARP14MAPT | |
| SCHEMBL28261376 | 0.91 | KIF11 (0.49) | TDO2IDO1KIF11PARP14MAPT | |
| SCHEMBL788300 | 0.91 | KIF11 (0.49) | TDO2IDO1KIF11PARP14MAPT | |
| SCHEMBL2781496 | 0.84 | IDO1 (0.48) | TDO2IDO1KIF11PARP14MAPT | |
| SCHEMBL38828 | 0.83 | KIF11 (0.57) | TDO2KIF11PARP14CDK4CCND1 | |
| SCHEMBL30641449 | 0.83 | KIF11 (0.57) | TDO2KIF11PARP14CDK4CCND1 | |
| SCHEMBL29407801 | 0.83 | KIF11 (0.57) | TDO2KIF11PARP14CDK4CCND1 | |
| SCHEMBL208888 | 0.83 | KIF11 (0.57) | TDO2KIF11PARP14CDK4CCND1 | |
| SCHEMBL1326376 | 0.83 | KIF11 (0.57) | TDO2KIF11PARP14CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102241698-B | Star-shaped triaryl borane compound and preparation method and application thereof | CHINESE ACAD TECH INST PHYSICS | 2013-12-25 | — | — | CN | disclosed |
| CN-102241698-A | Star-shaped triaryl borane compound and preparation method and application thereof | CHINESE ACAD TECH INST PHYSICS | 2011-11-16 | — | — | CN | disclosed |