Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678897 | 0.70 | TDP1 (0.32) | TDP1 | |
| SCHEMBL27861986 | 0.70 | EPHX1 (0.33) | — | |
| SCHEMBL4046388 | 0.70 | KDM4E (0.32) | — | |
| SCHEMBL13622561 | 0.69 | TDP1 (0.41) | TDP1 | |
| SCHEMBL1016198 | 0.69 | — | — | |
| SCHEMBL6141270 | 0.67 | — | — | |
| SCHEMBL27861925 | 0.66 | SIGMAR1 (0.46) | — | |
| SCHEMBL9728088 | 0.65 | — | — | |
| SCHEMBL5045442 | 0.65 | CA1 (0.45) | — | |
| SCHEMBL1308490 | 0.64 | GSR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102292319-A | Novel substituted octahydrocyclopenta(C)pyrrol-4-amines as calcium channel blockers | — | 2011-12-21 | — | — | CN | claimed |
| CN-102292319-A | Novel substituted octahydrocyclopenta(C)pyrrol-4-amines as calcium channel blockers | — | 2011-12-21 | — | — | CN | disclosed |