Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAC2 | P15153 | 1/20 | 0.49 |
| ▸ | RAC3 | P60763 | 1/20 | 0.49 |
| ▸ | CDC42 | P60953 | 1/20 | 0.49 |
| ▸ | RAC1 | P63000 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760446 | 0.83 | TSHR (0.71) | TSHRPTGS1PTGS2ALDH1A1HTT | |
| SCHEMBL1395472 | 0.83 | TSHR (0.70) | TSHRPTGS1PTGS2ALDH1A1HTT | |
| SCHEMBL28797468 | 0.82 | ALDH1A1 (0.49) | TSHRPTGS1PTGS2ALDH1A1HTT | |
| SCHEMBL28270531 | 0.79 | PTGS1 (0.61) | TSHRPTGS1PTGS2ALDH1A1HTT | |
| SCHEMBL27825639 | 0.79 | FLT3 (0.73) | TSHRPTGS1PTGS2ALDH1A1HTT | |
| SCHEMBL2898123 | 0.79 | FLT3 (0.73) | TSHRPTGS1PTGS2ALDH1A1HTT | |
| SCHEMBL11904310 | 0.77 | TSHR (0.71) | TSHRPTGS1PTGS2ALDH1A1HTT | |
| SCHEMBL12419436 | 0.75 | PTGS1 (0.57) | TSHRPTGS1PTGS2ALDH1A1HTT | |
| SCHEMBL20497362 | 0.74 | CDC7 (0.56) | TSHRCYP2C19TAAR1 | |
| SCHEMBL18865730 | 0.73 | TSHR (0.54) | TSHRALDH1A1HTTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102336719-B | Method for synthesizing 1,2,3-triazole compounds by utilizing sila-alkyne compounds | UNIV HAINAN NORMAL | 2014-05-28 | — | — | CN | claimed |
| CN-102336719-B | Method for synthesizing 1,2,3-triazole compounds by utilizing sila-alkyne compounds | UNIV HAINAN NORMAL | 2014-05-28 | — | — | CN | disclosed |
| CN-102336719-A | Method for synthesizing 1,2,3-triazole compounds by utilizing sila-alkyne compounds | UNIV HAINAN NORMAL | 2012-02-01 | — | — | CN | disclosed |