Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4580168 | 0.80 | MCL1 (0.55) | MCL1KMT2ACA9CA12KDM4E | |
| SCHEMBL12216196 | 0.76 | MRGPRX4 (0.46) | KMT2APOLBCA9CA12KDM4E | |
| SCHEMBL14010908 | 0.76 | CYP1A2 (0.43) | MCL1POLBCA9CA12KDM4E | |
| SCHEMBL29424659 | 0.76 | CA12 (0.63) | KMT2APOLBCA9CA12KDM4E | |
| SCHEMBL29145061 | 0.75 | KMT2A (0.39) | MCL1KMT2APOLBCA9CA12 | |
| SCHEMBL12216193 | 0.75 | MRGPRX4 (0.45) | KMT2ACA9CA12HSD17B10CA1 | |
| SCHEMBL30018039 | 0.73 | MCL1 (0.47) | MCL1KMT2ACA9CA12KDM4E | |
| SCHEMBL15834689 | 0.73 | MCL1 (0.38) | MCL1KMT2ACA9CA12KDM4E | |
| SCHEMBL16641215 | 0.71 | THRB (0.39) | KMT2ACA9CA12KDM4EHSD17B10 | |
| SCHEMBL12216195 | 0.71 | TYMS (0.41) | KMT2APOLBKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102382085-B | Benzofuran phenylpropanoids compound, preparation method and application thereof | UNIV YUNNAN NATIONALITIES | 2013-12-25 | — | — | CN | disclosed |
| CN-102382085-A | Benzofuran phenylpropanoids compound, preparation method and application thereof | UNIV YUNNAN NATIONALITIES | 2012-03-21 | — | — | CN | disclosed |