Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 10/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 10/20 | 0.51 |
| ▸ | SRC | P12931 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 6/20 | 0.43 |
| ▸ | LYN | P07948 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
| ▸ | GAK | O14976 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27862284 | 0.89 | BRAF (0.53) | BRAFMAPK14LMNAALDH1A1GAA | |
| SCHEMBL27844954 | 0.88 | BRAF (0.54) | BRAFMAPK14ABL1SRCLMNA | |
| SCHEMBL27844944 | 0.87 | ABL1 (0.50) | BRAFMAPK14ABL1SRCLMNA | |
| SCHEMBL27862199 | 0.83 | BRAF (0.51) | BRAFMAPK14ABL1LMNAALDH1A1 | |
| SCHEMBL27844947 | 0.83 | BRAF (0.53) | BRAFMAPK14ABL1LMNAALDH1A1 | |
| SCHEMBL27845105 | 0.83 | BRAF (0.52) | BRAFMAPK14ABL1LMNAALDH1A1 | |
| SCHEMBL27844997 | 0.82 | BRAF (0.57) | BRAFMAPK14KDRCA9 | |
| SCHEMBL27845008 | 0.82 | BRAF (0.51) | BRAFMAPK14LMNAALDH1A1GAA | |
| SCHEMBL27862197 | 0.81 | BRAF (0.55) | BRAFMAPK14KDR | |
| SCHEMBL27862531 | 0.80 | BRAF (0.52) | BRAFMAPK14KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250065-A | Substituted triazine phenyl urea derivatives and application thereof | ZHEJIANG HISUN PHARM CO LTD | 2011-11-23 | — | — | CN | disclosed |