Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 9/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27844954 | 0.93 | BRAF (0.54) | BRAFMAPK14MAPTMAPK1GAA | |
| SCHEMBL27862199 | 0.90 | BRAF (0.51) | BRAFMAPK14MAPTGAAALDH1A1 | |
| SCHEMBL27844947 | 0.89 | BRAF (0.53) | BRAFMAPK14MAPTGAAALDH1A1 | |
| SCHEMBL27845105 | 0.89 | BRAF (0.52) | BRAFMAPK14MAPTGAAKMT2A | |
| SCHEMBL27844945 | 0.89 | BRAF (0.50) | BRAFMAPK14MAPTMAPK1GAA | |
| SCHEMBL27844949 | 0.89 | BRAF (0.52) | BRAFMAPK14MAPTGAAALDH1A1 | |
| SCHEMBL27844997 | 0.88 | BRAF (0.57) | BRAFMAPK14TRPV1 | |
| SCHEMBL27845008 | 0.88 | BRAF (0.51) | BRAFMAPK14MAPTMAPK1GAA | |
| SCHEMBL27862197 | 0.86 | BRAF (0.55) | BRAFMAPK14TRPV1 | |
| SCHEMBL27862531 | 0.86 | BRAF (0.52) | BRAFMAPK14TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250065-A | Substituted triazine phenyl urea derivatives and application thereof | ZHEJIANG HISUN PHARM CO LTD | 2011-11-23 | — | — | CN | disclosed |