Methyl Alcohol

Methyl Alcohol

SCHEMBL27845136

CO.COC(=O)C1CCC(C(=O)O)CC1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.48
PTPN1 P18031 1/20 0.48
PPP1CC P36873 1/20 0.48
TP53 P04637 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.44
CHRNB2 P17787 2/20 0.42
CHRNA4 P43681 2/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
CHRNA7 P36544 1/20 0.42
PLG P00747 1/20 0.41
PLAT P00750 1/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 2/20 0.41
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
TSHR P16473 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145756 0.98 PPM1B (0.50) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL107582 0.98 PPM1B (0.50) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL595940 0.98 PPM1B (0.50) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL28306935 0.95 PPM1B (0.48) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL24195891 0.91 TP53 (0.48) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL22050976 0.91 SMN1; SMN2 (0.50) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL26627796 0.91 PPM1B (0.46) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
Methyl Alcohol SCHEMBL27845135 0.90 TP53 (0.54) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
Ethylene Glycol SCHEMBL1297362 0.89 PPM1B (0.44) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL19850749 0.88 SMN1; SMN2 (0.52) PPM1BPTPN1PPP1CCTP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102381938-A Method for preparing 1, 4-cyclohexanedimethanol PETROCHINA CO LTD 2012-03-21 CN disclosed