SCHEMBL145756

SCHEMBL145756

COC(=O)C1CCC(C(=O)O)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.50
PTPN1 P18031 1/20 0.50
PPP1CC P36873 1/20 0.50
TP53 P04637 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.46
CHRNB2 P17787 2/20 0.43
CHRNA4 P43681 2/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA7 P36544 1/20 0.43
PLG P00747 1/20 0.43
PLAT P00750 1/20 0.43
LMNA P02545 1/20 0.43
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
GABRA1 P14867 1/20 0.42
TSHR P16473 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRB3 P28472 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL595940 1.00 PPM1B (0.50) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL107582 1.00 PPM1B (0.50) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
Methyl Alcohol SCHEMBL27845136 0.98 PPM1B (0.48) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL28306935 0.98 PPM1B (0.48) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL24195891 0.93 TP53 (0.48) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL22050976 0.93 SMN1; SMN2 (0.50) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL26627796 0.93 PPM1B (0.46) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
Ethylene Glycol SCHEMBL1297362 0.91 PPM1B (0.44) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL19850749 0.91 SMN1; SMN2 (0.52) PPM1BPTPN1PPP1CCTP53SMN1; SMN2
SCHEMBL29254274 0.91 SMN1; SMN2 (0.56) PPM1BPTPN1PPP1CCTP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 989 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114789056-B Hydrogenation catalyst and preparation method and application thereof 中国科学院过程工程研究所 2024-07-12 CN claimed
CN-118206428-A Continuous preparation method and system of 1, 4-cyclohexanedimethanol and preparation method of Ni/Cu catalyst 上海戊正工程技术有限公司 2024-06-18 CN claimed
CN-118125917-A Preparation method of 1, 4-cyclohexanedimethanol intermediate 1, 4-cyclohexanedicarboxylic acid dimethyl ester 华东理工大学 2024-06-04 CN claimed
CN-118063314-A Method for preparing 1, 4-cyclohexanedicarboxylic acid dimethyl ester by hydrogenation of dimethyl terephthalate 华东理工大学 2024-05-24 CN claimed
CN-115304758-B Sulfur-containing polyester based on orcinol derivative, preparation and application 深圳万知达技术转移中心有限公司 2024-03-01 CN claimed
CN-117342952-A Method for reducing acid value in chemical raw material, prepared low-acid value chemical raw material and application 中国石油化工股份有限公司 2024-01-05 CN claimed
CN-117181238-A ruthenium-M bimetallic catalyst, preparation method thereof and application thereof in dimethyl terephthalate selective hydrogenation reaction 浙江恒逸石化研究院有限公司 2023-12-08 CN claimed
CN-117181218-A Catalyst for preparing 1, 4-cyclohexanedicarboxylic acid dimethyl ester from polyethylene terephthalate and application of catalyst 浙江恒逸石化研究院有限公司 2023-12-08 CN claimed
CN-112742389-B Catalyst for preparing 1, 4-cyclohexanedimethanol and preparation method and application thereof 常州大学 2023-11-17 CN claimed
CN-116943699-A Catalyst for preparing 1, 4-cyclohexanedicarboxylic acid dimethyl ester by hydrogenation of dimethyl terephthalate, and preparation method and application thereof 浙江恒逸石化研究院有限公司 2023-10-27 CN claimed
CN-111468112-B Catalyst for preparing 1, 4-cyclohexane dimethyl phthalate by selective hydrogenation of dimethyl terephthalate and preparation method thereof 西南化工研究设计院有限公司 2021-04-16 CN claimed
CN-111468112-A Catalyst for preparing 1, 4-cyclohexane dimethyl phthalate by selective hydrogenation of dimethyl terephthalate and preparation method thereof 西南化工研究设计院有限公司 2020-07-31 CN claimed
CN-110951064-A Phthalocyanine metal salt modified polyurethane elastomer and preparation method thereof 南通北风橡塑制品有限公司 2020-04-03 CN claimed
US-20120136152-A1 EFFICIENT SYNTHETIC METHOD OF 18F-MEFWAY PRECURSOR INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2012-05-31 US claimed
EP-1674496-B1 POLYESTER RESIN COMPOSITION AND OPTICAL MATERIAL OSAKA GAS CO LTD (JP) 2011-08-31 EP claimed
US-6794482-B2 Adhesion promoter additive comprising an unsaturated, amorphous polyester DEGUSSA AG (DE) 2004-09-21 US claimed
US-20040054075-A1 Adhesion promoter additive comprising an unsaturated, amorphous polyester DEGUSSA AG (DE) 2004-03-18 US claimed
EP-0656341-B1 Process for the production of cyclohexanedimethanol EASTMAN CHEM CO (US) 1998-04-22 EP claimed
EP-0656341-A1 Process for the production of cydohexanedimethanol EASTMAN CHEMICAL COMPANY (US) 1995-06-07 EP claimed
US-5414159-A Hydrogenation of dialkyl cyclohexanedicarboxylate to form cyclohexanedimethanol EASTMAN CHEMICAL COMPANY (US) 1995-05-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136152-A1 EFFICIENT SYNTHETIC METHOD OF 18F-MEFWAY PRECURSOR FTO, SLC7A5, CYP3A5 PPM1B 4092/4885PTPN1 4745/4885PPP1CC 4284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.