Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585894 | 1.00 | APP (0.45) | APPELANEHDAC1HDAC8HDAC6 | |
| SCHEMBL592017 | 1.00 | APP (0.45) | APPELANEHDAC1HDAC8HDAC6 | |
| SCHEMBL7780936 | 0.86 | HDAC1 (0.46) | ELANEHDAC1HDAC8HDAC6ACE | |
| SCHEMBL7782731 | 0.86 | HDAC1 (0.46) | ELANEHDAC1HDAC8HDAC6ACE | |
| SCHEMBL7779878 | 0.86 | HDAC1 (0.46) | ELANEHDAC1HDAC8HDAC6ACE | |
| SCHEMBL7779876 | 0.86 | HDAC1 (0.46) | ELANEHDAC1HDAC8HDAC6ACE | |
| SCHEMBL7775653 | 0.86 | HDAC1 (0.46) | ELANEHDAC1HDAC8HDAC6ACE | |
| SCHEMBL17138602 | 0.83 | ELANE (0.46) | ELANEHDAC1HDAC8HDAC6POLB | |
| SCHEMBL28613404 | 0.81 | ALDH1A1 (0.47) | ELANEHDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL13326693 | 0.80 | HDAC1 (0.46) | HDAC1HDAC8HDAC6POLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102388036-A | Serotonin and norepinephrine reuptake inhibitor | LILLY CO ELI | 2012-03-21 | — | — | CN | disclosed |