Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | GPR18 | Q14330 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2358849 | 0.86 | CDK2 (0.58) | CDK2CCNE2CCNE1PDPK1RPS6KB1 | |
| SCHEMBL20542116 | 0.74 | CCNE2 (0.49) | CDK2CCNE2CCNE1GPR18CNR1 | |
| SCHEMBL20542192 | 0.72 | CDK2 (0.52) | CDK2CCNE2CCNE1NPC1MAPK1 | |
| SCHEMBL20558018 | 0.71 | CDK1 (0.54) | CDK2CCNE2CCNE1TSHRCYP2C19 | |
| SCHEMBL20542182 | 0.71 | HTT (0.46) | CDK2CCNE2CCNE1GPR18CNR1 | |
| SCHEMBL30579436 | 0.71 | HTT (0.46) | CDK2CCNE2CCNE1GPR18CNR1 | |
| SCHEMBL30579381 | 0.71 | KMT2A (0.56) | CDK2PDPK1RPS6KB1MKNK1MKNK2 | |
| SCHEMBL21754368 | 0.71 | KMT2A (0.56) | CDK2PDPK1RPS6KB1MKNK1MKNK2 | |
| SCHEMBL29244477 | 0.70 | KMT2A (0.47) | PDPK1RPS6KB1KMT2AMEN1LMNA | |
| SCHEMBL29244533 | 0.70 | KMT2A (0.54) | CDK2PDPK1RPS6KB1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102203096-A | Compounds that expand hematopoietic stem cells | IRM LLC | 2011-09-28 | — | — | CN | disclosed |