Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 10/20 | 0.44 |
| ▸ | HTR1A | P08908 | 9/20 | 0.44 |
| ▸ | HTR7 | P34969 | 8/20 | 0.44 |
| ▸ | HTR6 | P50406 | 8/20 | 0.44 |
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29244423 | 0.90 | IP6K1 (0.49) | KMT2APOLBSLC2A1RAD52HTT | |
| SCHEMBL29244426 | 0.90 | IP6K1 (0.49) | KMT2APOLBSLC2A1RAD52HTT | |
| SCHEMBL29244421 | 0.90 | IP6K1 (0.49) | KMT2APOLBSLC2A1RAD52HTT | |
| SCHEMBL31535642 | 0.90 | IP6K1 (0.49) | KMT2APOLBSLC2A1RAD52HTT | |
| SCHEMBL30698037 | 0.90 | IP6K1 (0.49) | KMT2APOLBSLC2A1RAD52HTT | |
| SCHEMBL31535654 | 0.88 | KMT2A (0.45) | KMT2APOLBSLC2A1RAD52HTT | |
| SCHEMBL31535662 | 0.88 | KMT2A (0.45) | KMT2APOLBSLC2A1RAD52HTT | |
| SCHEMBL29244529 | 0.86 | KMT2A (0.47) | KMT2APOLBSLC2A1RAD52HTT | |
| SCHEMBL30278038 | 0.86 | KMT2A (0.47) | KMT2APOLBSLC2A1RAD52HTT | |
| SCHEMBL29244482 | 0.85 | KMT2A (0.50) | KMT2APOLBSLC2A1RAD52HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396191-B1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2026-02-18 | — | — | EP | disclosed |
| US-20250129092-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-04-24 | — | — | US | disclosed |
| EP-4396191-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-07-10 | — | — | EP | disclosed |
| CN-118076613-A | Compounds useful for modulating AhR signaling | 捷豹治疗有限公司 | 2024-05-24 | — | — | CN | disclosed |
| WO-2023033740-A9 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023033740-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2023-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129092-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | AHR, ARNT, AIPL1 | KMT2A 1548/4885POLB 4212/4885SLC2A1 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.