Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193602 | 0.91 | KMT2A (0.74) | KMT2ARAB9AMEN1MAPTTP53 | |
| SCHEMBL27977367 | 0.85 | SCD (0.61) | KMT2ARAB9AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL2192766 | 0.83 | SCD (0.56) | KMT2ARAB9AMEN1MAPTNPC1 | |
| SCHEMBL2000049 | 0.82 | SCD (0.59) | KMT2ARAB9AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL2196699 | 0.81 | MAPT (0.66) | KMT2ARAB9AMEN1MAPTTP53 | |
| SCHEMBL27846235 | 0.81 | MAPT (0.57) | KMT2ARAB9AMEN1MAPTTP53 | |
| SCHEMBL2196123 | 0.81 | SCD (0.57) | KMT2ARAB9AMEN1MAPTNPC1 | |
| SCHEMBL2191756 | 0.80 | SCD (0.72) | KMT2ARAB9AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL2195831 | 0.80 | SCD (0.56) | KMT2ARAB9AMEN1MAPTTP53 | |
| SCHEMBL1999194 | 0.80 | MAPT (0.64) | KMT2ARAB9AMEN1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102224423-B | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-10-22 | — | — | CN | disclosed |
| CN-102224423-A | Ligands for aggregated tau molecules | WISTA LAB LTD | 2011-10-19 | — | — | CN | disclosed |