Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 8/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983311 | 0.92 | MMP2 (0.69) | SCDRAB9AMEN1KMT2AMMP2 | |
| SCHEMBL2193602 | 0.90 | KMT2A (0.74) | SCDRAB9AMEN1KMT2AAPP | |
| SCHEMBL2000049 | 0.90 | SCD (0.59) | SCDRAB9AMEN1KMT2AAPP | |
| SCHEMBL2191756 | 0.88 | SCD (0.72) | SCDRAB9AMEN1KMT2AAPP | |
| SCHEMBL2196699 | 0.87 | MAPT (0.66) | SCDRAB9AMEN1KMT2AMMP2 | |
| SCHEMBL2196123 | 0.86 | SCD (0.57) | SCDRAB9AMEN1KMT2AAPP | |
| SCHEMBL2193132 | 0.86 | SCD (0.56) | SCDRAB9AMEN1KMT2AAPP | |
| SCHEMBL2195831 | 0.86 | SCD (0.56) | SCDRAB9AMEN1KMT2AAPP | |
| SCHEMBL1999194 | 0.86 | MAPT (0.64) | SCDRAB9AMEN1KMT2AAPP | |
| SCHEMBL2192766 | 0.86 | SCD (0.56) | SCDRAB9AMEN1KMT2AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102224423-B | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-10-22 | — | — | CN | disclosed |