SCHEMBL27848293

SCHEMBL27848293

CC(=O)OCN(Cc1ccc(F)cc1[N+](=O)[O-])C(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SNCA P37840 4/20 0.41
MAPT P10636 2/20 0.39
NR1D1 P20393 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27829874 0.85 SNCA (0.42) SNCAALDH1A1
SCHEMBL3429467 0.85 SNCA (0.42) SNCAMAPTNR1D1ALDH1A1
SCHEMBL3403008 0.83 SNCA (0.43) SNCAMAPTNR1D1L3MBTL1ALDH1A1
SCHEMBL16397397 0.77 MAPT (0.44) MAPTNR1D1L3MBTL1ALDH1A1
SCHEMBL5191594 0.75 SNCA (0.49) SNCAMAPTNR1D1ALDH1A1
SCHEMBL1264831 0.72 MAPT (0.41) SNCAMAPTNR1D1L3MBTL1ALDH1A1
SCHEMBL27848278 0.72 MAPT (0.38) SNCAMAPTNR1D1L3MBTL1ALDH1A1
SCHEMBL27822311 0.72 KMT2A (0.40) MAPTNR1D1L3MBTL1ALDH1A1
SCHEMBL30791431 0.71 HCAR3 (0.42) SNCAMAPTNR1D1L3MBTL1ALDH1A1
SCHEMBL27829838 0.71 HDAC3 (0.37) L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101925586-A Novel heterocyclic compounds PANACEA BIOTEC LTD 2010-12-22 CN disclosed