Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27848305 | 0.87 | NPC1 (0.44) | MEN1KMT2AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL28794160 | 0.84 | P2RY14 (0.43) | MEN1KMT2AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL27865414 | 0.84 | MET (0.43) | MEN1KMT2AALDH1A1TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27865341 | 0.83 | NPC1 (0.44) | MEN1KMT2AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL27848324 | 0.82 | HPGD (0.44) | KMT2AALDH1A1TP53SMN1; SMN2LMNA | |
| SCHEMBL27848415 | 0.80 | PPARG (0.43) | ALDH1A1SMN1; SMN2MAPTKDM4ENPC1 | |
| SCHEMBL27848329 | 0.80 | P2RY14 (0.42) | TP53SMN1; SMN2MAPTNPC1 | |
| SCHEMBL27865377 | 0.77 | PTPN2 (0.42) | MEN1KMT2AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL27865326 | 0.77 | DUSP1 (0.39) | MEN1KMT2AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL27848320 | 0.74 | NPC1 (0.43) | MEN1KMT2AALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102428080-A | Therapeutic or prophylactic agent for diseases in which neurotrophic factor activity participates | SUMITOMO CHEMICAL CO | 2012-04-25 | — | — | CN | disclosed |