SCHEMBL27848331

SCHEMBL27848331

Cc1n[nH]c(C(C)O)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.32
DYRK1A Q13627 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30300337 1.00 HCAR2 (0.32) HCAR2DYRK1A
SCHEMBL21736948 0.84 DYRK1A (0.33) DYRK1A
SCHEMBL13683202 0.74 PDE2A (0.32)
SCHEMBL16200363 0.70 P2RX7 (0.33)
SCHEMBL4347154 0.69
SCHEMBL1197102 0.67
SCHEMBL4361618 0.67
SCHEMBL13184190 0.67 HCAR2 (0.44) HCAR2DYRK1A
SCHEMBL28716897 0.64
SCHEMBL12465346 0.64 DYRK1A (0.48) DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102285971-A Pyrazolyl quinazolinone compound and application thereof 2011-12-21 CN disclosed