Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19992974 | 0.98 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1HTT | |
| Iodide SCHEMBL27807078 | 0.97 | TSHR (0.49) | TSHRTHRBDNM1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL27806996 | 0.97 | TSHR (0.56) | TSHRTHRBDNM1ALDH1A1HTT | |
| Bromide SCHEMBL27827598 | 0.97 | TSHR (0.51) | TSHRTHRBDNM1ALDH1A1HTT | |
| Fluoride Ion SCHEMBL27848852 | 0.97 | TSHR (0.51) | TSHRTHRBDNM1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL29257672 | 0.92 | TSHR (0.59) | TSHRTHRBDNM1HTT | |
| SCHEMBL6279632 | 0.92 | TSHR (0.59) | TSHRTHRBDNM1HTTLMNA | |
| Hydrochloric Acid SCHEMBL29257671 | 0.90 | TSHR (0.62) | TSHRTHRBDNM1HTT | |
| Hydrochloric Acid SCHEMBL28067877 | 0.90 | TSHR (0.62) | TSHRTHRBDNM1HTT | |
| Bromide SCHEMBL28079798 | 0.90 | TSHR (0.57) | TSHRDNM1HTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102349364-A | Electromagnetic wave shielding gel-like composition | 3M INNOVATIVE PROPERTIES CO | 2012-02-08 | — | — | CN | disclosed |